Bicalutamide

Pronunciation: BYE-ka-LOO-ta-mide
Generic Name: Bicalutamide
Brand Name: Casodex

Bicalutamide is used for:

Treating prostate cancer. Bicalutamide is used in combination with a luteinizing-hormone releasing hormone (LHRH) analog (eg, goserelin, leuprolide). It may also be used for other conditions as determined by your doctor.

Bicalutamide is a nonsteroidal antiandrogen. It works by blocking the action of testosterone.

Do NOT use Bicalutamide if:

• you are allergic to any ingredient in Bicalutamide


• you are a woman


• you are pregnant, planning to or may become pregnant, or are breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Bicalutamide:

Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have liver problems or diabetes

Some MEDICINES MAY INTERACT with Bicalutamide. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Oral anticoagulants (eg, warfarin) because the risk of side effects, including bleeding, may be increased


• Midazolam because the risk of its side effects may be increased by Bicalutamide.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bicalutamide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Bicalutamide:

Use Bicalutamide as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Bicalutamide. Talk to your pharmacist if you have questions about this information.


• Take Bicalutamide by mouth with or without food.


• Take Bicalutamide with your other prostate cancer medicine at the same time each day.


• If you miss a dose of Bicalutamide, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bicalutamide.

Important safety information:

• Bicalutamide may cause drowsiness or dizzinesss. These effects may be worse if you take it with alcohol or certain medicines. Use Bicalutamide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Serious and sometimes fatal liver problems have rarely occurred in patients who take Bicalutamide. Symptoms of liver problems may include dark urine, loss of appetite, nausea, pale stools, stomach pain, tiredness, vomiting, weakness, or yellowing of the eyes or skin. Contact your doctor immediately if you experience any of these symptoms.


• Bicalutamide may cause constipation or diarrhea. If you experience either constipation or diarrhea, ask your doctor or pharmacist to recommend a treatment for you.


• Diabetes patients - When used with LHRH analogs (eg, goserelin, leuprolide), Bicalutamide may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.


• Lab tests, including liver function, prostate-specific antigen (PSA), and blood sugar levels, may be performed while you use Bicalutamide. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Bicalutamide with caution in the ELDERLY; they may be more sensitive to its effects.


• Bicalutamide should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Bicalutamide is not approved for use in women. Do not use Bicalutamide if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Bicalutamide is found in breast milk. Do not breast-feed while taking Bicalutamide.

Possible side effects of Bicalutamide:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back, pelvic, stomach, or general body pain; constipation; decreased sexual ability; diarrhea; dizziness; frequent urination, especially at night; gas; headache; hot flashes; nausea; stomach upset; sweating; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; difficulty swallowing; unusual hoarseness); black or bloody stools; blurred vision or other vision changes; bone pain; breast growth or pain; changes in the amount of urine produced; chest pain; dark or bloody urine; fainting; fever, chills, or persistent sore throat; flu-like symptoms; increased hunger, thirst, or urination; joint pain, stiffness, or swelling; loss of appetite; mental or mood changes (eg, anxiety, depression); muscle aches or weakness; numbness or tingling of the skin; pale stools; severe or persistent cough; severe or persistent dizziness, drowsiness, or headache; severe or persistent nausea or stomach pain; shortness of breath; swelling of the ankles, legs, or feet; unusual bruising or bleeding; unusual tiredness or weakness; vomiting; weight change; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Bicalutamide side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Bicalutamide:

Store Bicalutamide at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bicalutamide out of the reach of children and away from pets.

General information:

• If you have any questions about Bicalutamide, please talk with your doctor, pharmacist, or other health care provider.


• Bicalutamide is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bicalutamide. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bicalutamide resources

• Bicalutamide Side Effects (in more detail)
• Bicalutamide Use in Pregnancy & Breastfeeding
• Drug Images
• Bicalutamide Drug Interactions
• Bicalutamide Support Group
• 5 Reviews for Bicalutamide - Add your own review/rating

• Bicalutamide Prescribing Information (FDA)


• Bicalutamide Professional Patient Advice (Wolters Kluwer)


• Bicalutamide Monograph (AHFS DI)


• bicalutamide Advanced Consumer (Micromedex) - Includes Dosage Information


• Casodex Prescribing Information (FDA)


• Casodex Consumer Overview

Compare Bicalutamide with other medications

• Prostate Cancer

Biperiden Hydrochloride

Class: Anticholinergic Agents
VA Class: AU350
CAS Number: 1235-82-1
Brands: Akineton

Introduction

Antimuscarinic antiparkinsonian agent.^{a b}

Uses for Biperiden Hydrochloride

Parkinsonian Syndrome

Adjunctive treatment of all forms of parkinsonian syndrome;^{a b} more efficacious in postencephalic and idiopathic cases than in arteriosclerotic types.^b

Relieves muscle rigidity, reduces sweating and salivation, improves gait, and to a lesser extent, tremor.^{a b}

Drug-Induced Extrapyramidal Reactions

Control of extrapyramidal reactions induced by neuroleptic agents (e.g., phenothiazines).^{a b}

Biperiden Hydrochloride Dosage and Administration

Administration

Oral Administration

Administer orally 1–3 times daily.^{a b}

Dosage

Available as biperiden hydrochloride, dosage expressed in terms of the salt.^a

Adjust dosage carefully according to individual requirements and response.^b

Adults

Parkinsonian Syndrome

Oral

Initially, 2 mg 3–4 times daily; if tolerance develops, or dosage is inadequate, titrate dose to maximum of 16 mg daily in 3–4 divided doses.^b

Drug-Induced Extrapyramidal Reactions

Oral

Usual dosage: 2 mg 1–3 times daily.^{a b}

Prescribing Limits

Adults

Oral

Maximum 16 mg daily.^{a b}

Special Populations

No special population dosage recommendations at this time.^a

Cautions for Biperiden Hydrochloride

Contraindications

• 
  

  Narrow angle glaucoma.^{a b}

  
  


• 
  

  Bowel obstruction or megacolon.^{a b}

  
  


• 
  

  Known hypersensitivity to biperiden or any ingredient in the formulation.^{a b}

  
  

Warnings/Precautions

Warnings

CNS Effects

Large or toxic doses or usual doses in patients with excess susceptibility may produce marked CNS disturbances (e.g., mental confusion, euphoria, agitation, disturbed behavior).^a

Use with caution in patients with epilepsy.^a

Ophthalmic Effects

Increased ocular tension associated with antimuscarinic use; however, such effect not reported with biperiden.^{a c} Use with caution in patients with glaucoma.^a

Cardiovascular Effects

Possible tachycardia; use with caution in patients with cardiac arrhythmias.^{a c}

GU Effects

Possible urinary retention; use with caution in patients with prostatic hypertrophy.^{a c}

Specific Populations

Pregnancy

Category C.^{a b}

Lactation

Not known whether biperiden is distributed into milk.^{a b} Caution advised if biperiden is used.^{a b}

Pediatric Use

Safety and efficacy not established.^a

Common Adverse Effects

Dry mouth, blurred vision, drowsiness, dizziness, constipation, agitation, mental confusion.^{a b}

Interactions for Biperiden Hydrochloride

Specific Drugs

Drug	Interaction	Comments
Alcohol	Possible additive CNS effectsa	Avoid concomitant usea
Anticholinergic agents	Increased risk of adverse anticholinergic effectsa b

Stability

Storage

Oral

Tablets

25°C (may be exposed to 15–30°C).^a Protect from light.^{a b}

ActionsActions

• 
  

  Exhibits atropine-like blocking action on parasympathetic-innervated peripheral structures, including smooth muscle.^a

  
  


• 
  

  Competitively inhibits acetylcholine or other cholinergic stimuli at autonomic effectors innervated by postganglionic nerves.^{a c}

  
  


• 
  

  Weak peripheral anticholinergic agent with antisecretory, antispasmodic, and mydriatic effects.^b

  
  


• 
  

  Exhibits nicotinolytic effects.^{a b} Nicotinolytic effects >6 times that of atropine.^b

  
  

Advice to Patients

• 
  

  Potential for drug to impair mental alertness or physical coordination; use caution when driving or operating machinery until effects on individual are known.^a

  
  


• 
  

  Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs and dietary or herbal supplements, as well as concomitant illnesses.^a

  
  


• 
  

  Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed.^a

  
  


• 
  

  Importance of informing patients of other important precautionary information. (See Cautions.)

  
  

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Biperiden Hydrochloride

Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Oral	Tablets	2 mg	Akineton (scored)	Abbott

Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions October 2007. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.

References

a. Par Pharmaceutical, Inc. Akineton (biperiden hydrochloride) tablets prescribing information. Spring Valley, NY; 2001 Nov.

b. AHFS drug information 2006. McEvoy GK, ed. Biperiden. Bethesda, MD: American Society of Health-System Pharmacists; 2006:1255.

c. AHFS drug information 2006. McEvoy GK, ed. Antimuscarinics/Antispasmodics General Statement. Bethesda, MD: American Society of Health-System Pharmacists; 2006:1257-64].

More Biperiden Hydrochloride resources

• Biperiden Hydrochloride Side Effects (in more detail)
• Biperiden Hydrochloride Dosage
• Biperiden Hydrochloride Use in Pregnancy & Breastfeeding
• Biperiden Hydrochloride Drug Interactions
• Biperiden Hydrochloride Support Group
• 0 Reviews for Biperiden Hydrochloride - Add your own review/rating

Compare Biperiden Hydrochloride with other medications

• Extrapyramidal Reaction
• Parkinson's Disease

Bio-Cef

Generic Name: cephalexin (Oral route)

sef-a-LEX-in

Commonly used brand name(s)

In the U.S.

• Bio-Cef


• Keflex


• Panixine DisperDose

In Canada

• Novo-Lexin

Available Dosage Forms:

• Tablet


• Capsule


• Tablet for Suspension


• Powder for Suspension

Therapeutic Class: Antibiotic

Pharmacologic Class: 1st Generation Cephalosporin

Uses For Bio-Cef

Cephalexin is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Before Using Bio-Cef

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of cephalexin in children.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cephalexin in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cephalexin.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Cholestyramine


• Metformin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Colitis (inflammation in gut), history of or


• Diarrhea, severe, history of—Use with caution. May make these conditions worse.

• Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.

Proper Use of cephalexin

This section provides information on the proper use of a number of products that contain cephalexin. It may not be specific to Bio-Cef. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Shake the oral liquid well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage forms (capsules or suspension):
  
  • For infections:
    
    • Adults and teenagers—The dose is 1000 to 4000 milligrams (mg) per day, taken in divided doses.
    
    
    • Children—Use and dose must be determined by your doctor. Dose is based on body weight and must be determined by your doctor. The dose is usually 25 to 100 milligrams (mg) per kilogram (kg) per day, taken in divided doses.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the capsules in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the oral liquid in the refrigerator. Throw away any unused medicine after 14 days.

Precautions While Using Bio-Cef

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Cephalexin may cause diarrhea, and in some cases it can be severe. Do not take any medicine or give medicine to your child to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Before you or your child have any medical tests, tell the medical doctor in charge that you are using this medicine. The results of some tests may be affected by this medicine.

Bio-Cef Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Diarrhea

Rare

• Abdominal or stomach pain


• blistering, peeling, or loosening of the skin


• chills


• clay-colored stools


• cough


• dark urine


• diarrhea


• dizziness


• fever


• general tiredness and weakness


• headache


• itching


• joint or muscle pain


• light-colored stools


• loss of appetite


• nausea and vomiting


• rash


• red skin lesions, often with a purple center


• red, irritated eyes


• sore throat


• sores, ulcers, or white spots in the mouth or on the lips


• unpleasant breath odor


• unusual tiredness or weakness


• upper right abdominal or stomach pain


• vomiting of blood


• yellow eyes or skin

Incidence not known

• Abdominal or stomach cramps or tenderness


• back or leg pains


• black, tarry stools


• bleeding gums


• bloating


• blood in the urine or stools


• chest pain


• coughing up blood


• diarrhea, watery and severe, which may also be bloody


• difficulty with breathing or swallowing


• fast heartbeat


• general body swelling


• hives


• increased menstrual flow or vaginal bleeding


• increased thirst


• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• loss of appetite


• nosebleeds


• pain


• painful or difficult urination


• pale skin


• paralysis


• pinpoint red spots on the skin


• prolonged bleeding from cuts


• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue


• red or black, tarry stools


• red or dark brown urine


• shortness of breath


• swollen or painful glands


• tightness in the chest


• unusual bleeding or bruising


• unusual weight loss


• watery or bloody diarrhea


• wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Acid or sour stomach


• anxiety


• belching


• burning feeling in the chest or stomach


• difficulty with moving


• dry mouth


• heartburn


• hives or welts


• hyperventilation


• indigestion


• irregular heartbeats


• irritability


• itching of the vagina or genital area


• muscle pain or stiffness


• nervousness


• pain during sexual intercourse


• pain, swelling, or redness in the joints


• redness of the skin


• restlessness


• seeing, hearing, or feeling things that are not there


• shaking


• stomach upset


• trouble with sleeping


• white or brownish vaginal discharge

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Bio-Cef side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Bio-Cef resources

• Bio-Cef Side Effects (in more detail)
• Bio-Cef Use in Pregnancy & Breastfeeding
• Drug Images
• Bio-Cef Drug Interactions
• Bio-Cef Support Group
• 0 Reviews for Bio-Cef - Add your own review/rating

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• Acne
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• Bacterial Infection
• Bladder Infection
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• Kidney Infections
• Otitis Media
• Pharyngitis
• Prostatitis
• Skin Infection
• Upper Respiratory Tract Infection

Bio-Statin Powder

Pronunciation: nye-STA-tin
Generic Name: Nystatin
Brand Name: Bio-Statin

Bio-Statin Powder is used for:

Treatment of fungal infections of the mouth and intestines. It may also be used for other conditions as determined by your doctor.

Bio-Statin Powder is an antifungal. It works by weakening cell membranes of the sensitive fungus. This allows the cell contents to leak out and results in death of the fungus.

Do NOT use Bio-Statin Powder if:

• you are allergic to any ingredient in Bio-Statin Powder

Contact your doctor or health care provider right away if any of these apply to you.

Before using Bio-Statin Powder:

Some medical conditions may interact with Bio-Statin Powder. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Bio-Statin Powder. However, no specific interactions with Bio-Statin Powder are known at this time.

Ask your health care provider if Bio-Statin Powder may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Bio-Statin Powder:

Use Bio-Statin Powder as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• Place the amount of Bio-Statin Powder prescribed by your doctor in 4 to 6 ounces of water. Stir until all of the medicine is dissolved.


• If the mouth is affected, place half the dose in each side of the mouth. Swish the medicine around the entire mouth. Retain the dose in your mouth as long as possible before swallowing, unless directed otherwise by your doctor.


• Take your dose immediately after mixing the medicine. Do not store mixed medicine for use at a later time.


• Bio-Statin Powder works best if it is taken at the same time every day.


• To clear up your infection completely, take Bio-Statin Powder for the full course of treatment. Keep taking it even if you feel better in a few days.


• If you miss a dose of Bio-Statin Powder, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bio-Statin Powder.

Important safety information:

• Practice good oral hygiene, including proper care of dentures, while you are taking Bio-Statin Powder.


• Be sure to use Bio-Statin Powder for the full course of treatment. If you do not, the medicine may not clear up your infection completely.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Bio-Statin Powder while you are pregnant. It is not known if Bio-Statin Powder is found in breast milk. If you are or will be breast-feeding while you use Bio-Statin Powder, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Bio-Statin Powder:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; nausea; stomach irritation; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Bio-Statin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea; high blood pressure; nausea; serious irregular heartbeat; vomiting; wheezing.

Proper storage of Bio-Statin Powder:

Store Bio-Statin Powder in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Throw away any unused medicine 90 days after the container is first opened. Keep Bio-Statin Powder out of the reach of children and away from pets.

General information:

• If you have any questions about Bio-Statin Powder, please talk with your doctor, pharmacist, or other health care provider.


• Bio-Statin Powder is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bio-Statin Powder. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bio-Statin resources

• Bio-Statin Side Effects (in more detail)
• Bio-Statin Use in Pregnancy & Breastfeeding
• Bio-Statin Drug Interactions
• Bio-Statin Support Group
• 0 Reviews for Bio-Statin - Add your own review/rating

Compare Bio-Statin with other medications

• Gastrointestinal Candidiasis
• Oral Thrush

Bilberry

Pronunciation: Not applicable.
Generic Name: Bilberry
Brand Name: Generics only. No brands available.

Bilberry is used for:

Eye conditions, including night blindness, diabetic retinopathy, glaucoma, and cataracts; to decrease blood clotting; and for hemorrhoids. It is also promoted to improve circulation conditions in patients with varicose veins and atherosclerosis. Bilberry has been used for diarrhea, especially mild cases. It may have other uses as well. Check with your pharmacist for more details regarding the particular brand you use.

Bilberry is an herbal product. A substance in bilberry fruit strengthens capillary resistance and helps protect capillaries from damage by free radicals.

Do NOT use Bilberry if:

• you are allergic to any ingredient in Bilberry


• you are taking disulfiram (applies to bilberry liquid extracts or tinctures only)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Bilberry:

Some medical conditions may interact with Bilberry. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have diabetes

Some MEDICINES MAY INTERACT with Bilberry. However, no specific interactions are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bilberry may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Bilberry:

Use Bilberry as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Bilberry may be taken with food if it upsets your stomach.


• Dosing depends on the use and the source of the product.


• Use as directed on the package, unless instructed otherwise by your doctor.


• If you miss taking a dose of Bilberry for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day.

Ask your health care provider any questions you may have about how to use Bilberry.

Important safety information:

• If you are taking this product for diarrhea and your symptoms do not improve within 3 or 4 days, contact your doctor. The fresh berries of bilberry extract produce a laxative effect and should not be used to treat diarrhea.


• This product has not been approved by the Food and Drug Administration (FDA) as safe and effective for any medical condition. The long-term safety of herbal products is not known. Before using any alternative medicine, talk with your doctor or pharmacist.


• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using this product.


• Diabetes patients - Bilberry extracts may lower your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.


• Use Bilberry with caution in CHILDREN.


• PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the risks of using this product during pregnancy. If you are or will be breast-feeding while you are using this product, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Bilberry:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dry eyes; dry mouth; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Bilberry side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include unexplained weight loss or weakness; unusual tiredness; yellowing of the skin or eyes.

Proper storage of Bilberry:

Store at room temperature away from heat, moisture, and light unless otherwise directed on the package label. Do not store in the bathroom. Most herbal products are not in childproof containers. Keep Bilberry out of the reach of children and away from pets.

General information:

• If you have any questions about Bilberry, please talk with your doctor, pharmacist, or other health care provider.


• Bilberry is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bilberry. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bilberry resources

• Bilberry Side Effects (in more detail)
• Bilberry Use in Pregnancy & Breastfeeding
• Bilberry Support Group
• 0 Reviews for Bilberry - Add your own review/rating

• Bilberry Natural MedFacts for Professionals (Wolters Kluwer)


• Bilberry Natural MedFacts for Consumers (Wolters Kluwer)


• bilberry Concise Consumer Information (Cerner Multum)

Compare Bilberry with other medications

• Dermatitis
• Diarrhea
• Diarrhea, Acute
• Eczema
• Gout
• Herbal Supplementation
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• Skin Rash
• Tonsillitis/Pharyngitis
• Urinary Tract Infection

Bidex 400

Generic Name: guaifenesin (Oral route)

gwye-FEN-e-sin

Commonly used brand name(s)

In the U.S.

• Allfen


• Altarussin


• Amibid LA


• Antitussin


• Bidex 400


• Diabetic Siltussin DAS-Na


• Diabetic Tussin EX


• Drituss G


• Guaifenex G


• Guaifenex LA


• Mucinex


• Robitussin

In Canada

• Benylin-E


• Benylin E Extra Strength Chest Congestion


• Broncho-Grippex Expectorant


• Robitussin Extra Strength

Available Dosage Forms:

• Tablet, Extended Release


• Solution


• Capsule, Extended Release


• Packet


• Liquid


• Tablet


• Capsule


• Elixir


• Syrup

Therapeutic Class: Expectorant

Uses For Bidex 400

Guaifenesin is used to help clear mucus or phlegm (pronounced flem) from the chest when you have congestion from a cold or flu. It works by thinning the mucus or phlegm in the lungs.

This medicine is available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Before Using Bidex 400

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of guaifenesin in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults. However, check with your doctor before using this medicine in children who have a chronic cough, such as occurs with asthma, or who have an unusually large amount of mucus or phlegm with the cough. Children with these conditions may need a different kind of medicine. Also, guaifenesin should not be given to children and infants younger than 2 years of age unless you are directed to do so by your doctor.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of guaifenesin in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of guaifenesin

This section provides information on the proper use of a number of products that contain guaifenesin. It may not be specific to Bidex 400. Please read with care.

Drinking plenty of water while taking guaifenesin may help loosen mucus or phlegm in the lungs.

For patients taking the extended-release capsule form of this medicine:

• Swallow the capsule whole, or open the capsule and sprinkle the contents on soft food such as applesauce, jelly, or pudding and swallow without crushing or chewing.

For patients taking the extended-release tablet form of this medicine:

• If the tablet has a groove in it, you may carefully break it into two pieces along the groove. Then swallow the pieces whole, without crushing or chewing them.


• If the tablet does not have a groove, it must be swallowed whole. Do not break, crush, or chew it before swallowing.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For regular (short-acting) oral dosage forms (capsules, oral solution, syrup, or tablets):
  
  • For cough:
    
    • Adults—200 to 400 milligrams (mg) every four hours.
    
    
    • Children 6 to 12 years of age—100 to 200 mg every four hours.
    
    
    • Children 4 to 6 years of age—50 to 100 mg every four hours.
    
    
    • Children and infants up to 4 years of age—Use is not recommended .
    
    
  
  


• For long-acting oral dosage forms (extended-release capsules or tablets):
  
  • For cough:
    
    • Adults—600 to 1200 mg every twelve hours.
    
    
    • Children 6 to 12 years of age—600 mg every twelve hours.
    
    
    • Children 4 to 6 years of age—300 mg every twelve hours.
    
    
    • Children and infants up to 4 years of age—Use is not recommended .
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Bidex 400

If your cough has not improved after 7 days or if you have a fever, skin rash, continuing headache, or sore throat with the cough, check with your doctor. These signs may mean that you have other medical problems.

Bidex 400 Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

• Diarrhea


• dizziness


• headache


• hives


• nausea or vomiting


• skin rash


• stomach pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Bidex 400 side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Bidex 400 resources

• Bidex 400 Side Effects (in more detail)
• Bidex 400 Use in Pregnancy & Breastfeeding
• Bidex 400 Support Group
• 0 Reviews for Bidex 400 - Add your own review/rating

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• Bronchitis
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Biopatch

Generic Name: chlorhexidine topical (klor HEX i deen TOP i kal)

Brand Names: Betasept, Biopatch, Calgon Vesta, Chlorostat, Chlorostat 4, Dyna-Hex, Hibiclens, PerioChip, Spectrum-4

What is Biopatch (chlorhexidine topical)?

Chlorhexidine is an antiseptic that fights bacteria.

Chlorhexidine topical (for the skin) is used to clean the skin to prevent infection that may be caused by surgery, injection, or skin injury.

Chlorhexidine topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Biopatch (chlorhexidine topical)?

You should not use chlorhexidine topical if you are allergic to it.

Ask a doctor or pharmacist if it is safe for you to use chlorhexidine topical if you have any allergies to food, dyes, animals, or medicines.

Avoid getting this medication in your eyes, ears, nose, mouth, rectum, or vagina. Chlorhexidine topical is for use only on the skin.

Stop using the medication and call your doctor if you have a skin reaction such as severe burning, itching, redness, blistering, peeling, swelling, rash, or any other severe irritation.

What should I discuss with my health are provider before using Biopatch (chlorhexidine topical)?

You should not use chlorhexidine topical if you are allergic to it.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have any allergies to food, dyes, animals, or medicines.

FDA pregnancy category C. It is not known whether chlorhexidine topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether chlorhexidine topical passes into breast milk or if it could harm a nursing baby. Do not breast-feed if you are using this medicine to treat a skin condition in the breast area. Chlorhexidine topical should not be used on a child younger than 2 months old.

How should I use Biopatch (chlorhexidine topical)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Rinse the skin before applying chlorhexidine topical gel or dressing. Apply only enough to cover the area you are treating.

To use chlorhexidine topical soap, apply only enough to cover the area you are treating. Wash the area gently, then rinse thoroughly with plain water. Avoid using over large areas of skin.

Do not apply this medication to deep cuts, scrapes, or open skin wounds. Chlorhexidine topical can also be harmful if it gets in your eyes, ears, mouth, nose, rectum, or vagina.

Call your doctor if your symptoms do not improve, or if they get worse while using chlorhexidine topical.

Some forms of this medicine are flammable. Do not use while you are smoking, or near high heat or open flame. Store at room temperature away from moisture, heat, and light. Do not freeze. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Biopatch (chlorhexidine topical)?

Avoid getting this medication in your eyes, ears, nose, mouth, rectum, or vagina. If this does happen, rinse with water. Chlorhexidine topical is for use only on the skin.

Avoid using other medications on the areas you treat with chlorhexidine topical unless you doctor tells you to.

Avoid getting this medication on your clothing or other fabrics. Do not use bleach to wash any fabric exposed to chlorhexidine or the medicine may cause a permanent stain.

Biopatch (chlorhexidine topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using chlorhexidine topical and call your doctor at once if you have a serious side effect such as:

• 
  

  severe burning, itching, or redness;

  
  


• 
  

  blistering or peeling;

  
  


• 
  

  swelling or severe skin rash; or

  
  


• 
  

  any other severe irritation of treated skin.

  
  

Less serious side effects may occur, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Biopatch (chlorhexidine topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied chlorhexidine topical. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Biopatch resources

• Biopatch Side Effects (in more detail)
• Biopatch Use in Pregnancy & Breastfeeding
• Biopatch Support Group
• 0 Reviews for Biopatch - Add your own review/rating

• Betasept Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Betasept Advanced Consumer (Micromedex) - Includes Dosage Information


• Peridex Prescribing Information (FDA)


• Peridex Advanced Consumer (Micromedex) - Includes Dosage Information


• Peridex Solution MedFacts Consumer Leaflet (Wolters Kluwer)


• PerioGard Prescribing Information (FDA)


• Periochip Prescribing Information (FDA)

Compare Biopatch with other medications

• Gingivitis
• Mucositis
• Periodontitis

Where can I get more information?

• Your pharmacist can provide more information about chlorhexidine topical.

See also: Biopatch side effects (in more detail)